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Biofilms, complex communities of microorganisms encased in a self-produced extracellular matrix, are notorious for their resilience and resistance to conventional antimicrobial therapies. They are a significant cause of chronic infections and pose a substantial challenge in clinical settings, particularly in patients with implantable devices or compromised immune systems. Biofilms cause resistance to many antimicrobial agents. The result of indwelling biofilms on medical devices is recurring, untreatable infections and medical device failure. To overcome chronic and recurrent infections, it is important to detect microbial biofilms and determine their antimicrobial susceptibility. In addition, identifying genes involved in biofilm formation and measuring gene expression due to anti-biofilm and antibacterial activity of agents may be beneficial in biofilm research.

C. elegans has long been a workhorse of genetic studies owing to its simple anatomy, sequenced genome, and rapid life cycle. Nevertheless, there has been a dearth of high-quality C. elegans genotyping tools, which has hindered experimental accuracy and reproducibility. CD BioSciences addresses this gap with its C. elegans Lysis Kits, which provide streamlined protocols and robust kits that ensure superior performance in C. elegans genotyping.

The Synthetic Biology Platform is a comprehensive toolbox and fully integrated platform to empower synthetic biology research and development.

To facilitate the research and development of synthetic biology, a one-stop synthetic biology platform is developed to offer comprehensive tools and resources for DNA synthesis, gene editing, enzyme discovery, and so forth. From design to build, test, and learn, this platform covers every aspect of the synthetic biology project lifecycle—simplifying researchers’ journey to groundbreaking discoveries with unified, cutting-edge solutions.

Fluorescent nanodiamonds (FNDs) are emerging as efficient and safe candidates for cellular imaging, due to their bright fluorescence, high photostability with sufficiently long lifetime, and excellent biocompatibility. For in vivo work, FNDs have been recognized as a safe and biocompatible material in many studies. Amerigo Scientific provides nanodiamonds featuring three distinct fluorescence properties: NV centers emitting red-to-near-infrared fluorescence, NVN centers exhibiting green fluorescence, and novel hybrid particles containing both NV and NVN centers within a single structure, which display visible yellow fluorescence. These hybrid particles enable ratiometric fluorescence calibration by monitoring the intensity ratio between green and red spectral emissions. This capability facilitates particle tracking even under conditions of high background fluorescence.

In today’s fast-moving world of cell biology, there is a need for reliable and reproducible analysis of cell proliferation and viability to progress research in drug discovery, cancer studies, and regenerative medicine. Realizing that this is a critical need, Amerigo Scientific has just introduced its expanding line of cell proliferation and viability assay kits which offer a performance that is bound to revolutionize cell-based assays for drug discovery researchers, immunologists, and regenerative medicine specialists.

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